3rd October 2014: Supported in part by OxSynC, Prof David Hodgson (Chemistry) and Dr Kenny Moore (Pathology) collaborated to test Hyperolactone C and analogues as potential inhibitors of HIV-1 replication. This work has recently been reported in the Journal of Organic Chemistry.
24th July 2014: Work by OxSynC collaborators Mark Howarth (Biochemistry) and Prof Tim Donohoe (Chemistry) has recently been published in Bioorganic and Medicinal Chemistry: Love-Hate ligands for high resolution analysis of strain in ultra-stable protein/small molecule interactions.
1st April 2014: Following discussions initiated through OxSynC, Veronica Buckle (Weatherall Institute of Molecular Medicine) and Thomas Brown (Chemistry) have been awarded a grant from BBSRC to fund a joint postdoctoral research assistance to synthesise new fluorescent probes for labelling nucleic acids.
20th November 2012: OxSynC will be presenting at the Begbroke coffee morning on the 28th November.
15th October 2012: The Autumn 2012 newsletter is now available.
5th October 2012: OxSynC awarded a 6 month PDRA grant.
3rd October 2012: OxSynC host 2nd drop-in session at the WIMM.
23rd September 2012: Introduction to OxSynC presentation at the Department of Physiology, Anatomy and Genetics.
5th September 2012: OxSynC host 1st drop-in session at the WIMM.
6th July 2012: OxSynC members attend seminar at the Weatherall Institute of Molecular Medicine.
26th June 2012: Third collaborative project between Timothy Donohoe (Chemistry) and Mark Howarth (Biochemistry). Project title: Understanding mechanical forces that affect protein-ligand interactions.
21st June 2012: Introduction to OxSynC presentation at the British Heart Foundation Centre for Research Excellence.
12th June 2012: Introduction to OxSynC presentation at the Pharmacology Department.
8th June 2012: Second collaborative project between Jeremy Robertson (Chemistry) and Stephen Hesselbo (Earth Sciences) has been approved for seed funding. Project title: Development of lignin degradation method.
30th April 2012: Introduction to OxSynC presentation at the Weatherall Institute of Molecular Medicine.
16th April 2012: First collaborative project between Angela Russell (Chemistry) and Eric O'Neill (Oncology) has been approved for seed funding. Project title: Synthesis of Small Molecule Modulators of the Hippo Signalling Pathway
Other networks from across the chemistry department or involving synthetic chemistry:
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